JPMorgan’s Marko Kolanovic has the highest 2021 S&P target on the Street. He joins the desk to tell us what’s going to get it there. Plus, Bitcoin hitting a new record above $20,000 for the first time, and our Bitcoin Baller thinks there are a couple reasons the rally has only just begun.

The first coronavirus vaccines are rolling out across the country, but a rising death toll and the threat of more lockdowns kept the reopening trade in check today. Are we in for a rough ride for markets over the next few months. Plus we’re on the frontlines with a look at the particular difficulties in getting the vaccines out to those who need them.