Like tens of millions of people, Stephen Dubner thought he had a penicillin allergy. Like the vast majority, he didn’t. This misdiagnosis costs billions of dollars and causes serious health problems, so why hasn’t it been fixed? And how about all the other things we think we’re allergic to?   SOURCES:Kimberly Blumenthal, allergist-immunologist and researcher at Mass General Hospital and Harvard Medical School.Theresa MacPhail, associate professor of science and technology studies at Stevens Institute of Technology.Thomas Platts-Mills, professor of medicine at the University of Virginia.Elena Resnick, allergist and immunologist at Mount Sinai Hospital.  RESOURCES:Allergic: Our Irritated Bodies in a Changing World, by Theresa MacPhail (2023)."Evaluation and Management of Penicillin Allergy: A Review," by Erica S. Shenoy, Eric Macy, and Theresa Rowe (JAMA, 2019)."The Allergy Epidemics: 1870–2010," by Thomas Platts-Mills (The Journal of Allergy and Clinical Immunology, 2016)."Randomized Trial of Peanut Consumption in Infants at Risk for Peanut Allergy," by George Du Toit, Graham Roberts, et al. (The New England Journal of Medicine, 2015).  EXTRAS:Freakonomics, M.D.

Probably not — the incentives are too strong. But a few reformers are trying. We check in on their progress, in an update to an episode originally published last year. (Part 2 of 2)   SOURCES:Max Bazerman, professor of business administration at Harvard Business School.Leif Nelson, professor of business administration at the University of California, Berkeley Haas School of Business.Brian Nosek, professor of psychology at the University of Virginia and executive director at the Center for Open Science.Ivan Oransky, distinguished journalist-in-residence at New York University, editor-in-chief of The Transmitter, and co-founder of Retraction Watch.Joseph Simmons, professor of applied statistics and operations, information, and decisions at the Wharton School at the University of Pennsylvania.Uri Simonsohn, professor of behavioral science at Esade Business School.Simine Vazire, professor of psychology at the University of Melbourne and editor-in-chief of Psychological Science.  RESOURCES:"How a Scientific Dispute Spiralled Into a Defamation Lawsuit," by Gideon Lewis-Kraus (The New Yorker, 2024)."The Harvard Professor and the Bloggers," by Noam Scheiber (The New York Times, 2023)."They Studied Dishonesty. Was Their Work a Lie?" by Gideon Lewis-Kraus (The New Yorker, 2023)."Evolving Patterns of Extremely Productive Publishing Behavior Across Science," by John P.A. Ioannidis, Thomas A. Collins, and Jeroen Baas (bioRxiv, 2023)."Hindawi Reveals Process for Retracting More Than 8,000 Paper Mill Articles," (Retraction Watch, 2023)."Exclusive: Russian Site Says It Has Brokered Authorships for More Than 10,000 Researchers," (Retraction Watch, 2019)."How Many Scientists Fabricate and Falsify Research? A Systematic Review and Meta-Analysis of Survey Data," by Daniele Fanelli (PLOS One, 2009).Lifecycle Journal.  EXTRAS:"Why Is There So Much Fraud in Academia? (Update)" by Freakonomics Radio (2024)."Freakonomics Goes to College, Part 1," by Freakonomics Radio (2012).