As more and more L2s launch promising to scale Ethereum, they end up competing for the same market share, userbase and liquidity. Apart from this harsh reality, crosschain interactions should be as seamless as possible in order to bridge different L2 ecosystems. Polygon envisions a scalable future in which various zero knowledge rollups post their proofs on an aggregation layer before settling on Ethereum, thus lowering latency and transaction costs as crosschain interactions take place expeditiously, without involving the L1 mainnet. We were joined by Sandeep Nailwal & Brendan Farmer, to discuss Polygon’s aggregation layer and how it aims to solve the current fragmentation of Ethereum L2 scaling solutions. Topics covered in this episode: Polygon’s ZK expansion and the acquisition of Mir ProtocolPolygon’s aggregation layerBlock building between different L2sShared sequencing & asynchronous sequencingSecurity guarantees of the aggregation layerSequencer decentralisation & censorship resistanceChains using Polygon’s aggregation layerPessimistic proofsCan optimistic rollups be included in the aggregation layer?Type 1 prover and Plonky3The evolution of ZKP systemsEnsuring ZK rollup integrityThe future of scalabilityEpisode links: Sandeep Nailwal on TwitterBrendan Farmer on TwitterPolygon on TwitterSponsors: Gnosis: Gnosis builds decentralized infrastructure for the Ethereum ecosystem, since 2015. This year marks the launch of Gnosis Pay— the world's first Decentralized Payment Network. Get started today at - gnosis.ioChorus One: Chorus One is one of the largest node operators worldwide, supporting more than 100,000 delegators, across 45 networks. The recently launched OPUS allows staking up to 8,000 ETH in a single transaction. Enjoy the highest yields and institutional grade security at - chorus.oneThis episode is hosted by Friederike Ernst.

One could argue that psychedelic research has experienced a similar journey as crypto, in the sense that decentralised communities bound together to fund research where centralised entities refuse to do so. One of the greatest hurdles in modern science is access to research funding, and DeSci aims to provide a solution through decentralised crowdfunding. In addition, IP rights are incontestably attributed with the help of blockchain technology, as they cannot be altered at a later date. However, as the human mind is unique and moulded by each individual’s life story, establishing a causal relationship between consumption and their beneficial or detrimental effects can be extremely biased. We were joined by Dima Buterin & Paul Kohlhaas, to discuss the vast subject of psychedelics (especially in relationship to trauma), how research has progressed and how decentralisation pushes the field forward (DeSci). Topics covered in this episode: Dima’s & Paul’s backgroundsDiscovering psychedelicsDealing with traumaPsychedelics throughout history and societiesHow Molecule DAO was foundedDeSci & on-chain IPEthereum early days, causality & rationalityPsyDAONetwork statesMiscEpisode links: Dima Buterin on TwitterPaul Kohlhaas on TwitterMolecule DAO on TwitterPsy DAO on TwitterSponsors: Gnosis: Gnosis builds decentralized infrastructure for the Ethereum ecosystem, since 2015. This year marks the launch of Gnosis Pay— the world's first Decentralized Payment Network. Get started today at - gnosis.ioChorus One: Chorus One is one of the largest node operators worldwide, supporting more than 100,000 delegators, across 45 networks. The recently launched OPUS allows staking up to 8,000 ETH in a single transaction. Enjoy the highest yields and institutional grade security at - chorus.oneThis episode is hosted by Brian Fabian Crain.