Ukraine gets U.S. approval to fire long-range missiles into Russia, raising the stakes in a war that's entering a harsh winter. President Biden pushes his climate agenda at the G20 summit in Brazil, seeking to solidify U.S. leadership as allies prepare for President-elect Trump's return. And, Trump's plan to combat the fentanyl crisis sparks debate over whether tougher crackdowns on traffickers will help or harm efforts to save lives. Your feedback helps us make Up First better. Tell us what you like and what you don't like by taking our survey at npr.org/upfirstsurvey Want more comprehensive analysis of the most important news of the day, plus a little fun? Subscribe to the Up First newsletter. Today's episode of Up First was edited by Andrew Sussman, Tara Neill, Andrea DeLeon, Mohamad ElBardicy, and Alice Woelfle.It was produced by Ziad Buchh, Nia Dumas and Milton Guevara.We get engineering support from Arthur Laurent. And our technical director is Zac Coleman. Learn more about sponsor message choices: podcastchoices.com/adchoices NPR Privacy Policy

What do President-elect Donald Trump's picks for his national security team say about his 2nd term priorities? New data shows a slight decline in sexually transmitted infections. The latest from the UN Climate Change Conference in Azerbaijan. Learn more about sponsor message choices: podcastchoices.com/adchoices NPR Privacy Policy