Facing off with the FTC isn't for the timid. But when your mission and your business model are aligned, the hard decisions – about risk, about investment, about priorities – become clearer. Francis deSouza is CEO of Illumina, the world’s dominant maker of gene sequencing technology. After playing a key role in the creation of Covid vaccines, Illumina is trying to acquire a company with a breakthrough cancer screening test, over the FTC's objections. DeSouza offers a personal reflection on the lessons and reality of grappling with regulators, highlighting levers that can help to accelerate scale. What underscores his entrepreneurial efforts is a passion for Illumina’s mission: improving human health by unlocking the power of the genome. Read a transcript of this interview at: mastersofscale.com Subscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribe See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

What can entrepreneurs learn from a genre-crossing, multi-platinum musician? How to take a big opportunity — and leverage it into something epic. From his earliest days as a founding member of the Black Eyed Peas, will.i.am learned from mentors how to not only identify big opportunities but compound them. From the Super Bowl to the first iTunes commercial; from the founding of Beats and his tech company i.am+ to a song beamed back from Mars, his ability to bring stakeholders together to leverage partnerships and compound possibilities will inspire founders at any stage of scale. Cameo appearance: Jeremy Siegel (urban designer, Bjarke Ingels Group). Read a transcript of this episode: https://mastersofscale.com Subscribe to the Masters of Scale weekly newsletter: https://mastersofscale.com/subscribe See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.