Bad news: 93% of Americans are metabolically unhealthy. Their bodies struggle to convert food into the energy their cells need. And this fuel shortage underlies all sorts of conditions, from diabetes and cancer to insomnia and erectile dysfunction. Good news: Simple changes to how we eat and exercise can dramatically improve our metabolic health. This is the thesis of “Good Energy: The Surprising Connection Between Metabolism and Limitless Health” by Casey Means. A Stanford-trained physician, Casey grew disillusioned with conventional healthcare when she realized that many doctors are great at prescribing pills and performing surgeries but hopeless when it comes to addressing root causes. This led her to leave traditional medicine and focus on combating metabolic dysfunction, which she believes is at the heart of America’s health crisis. Today on the show, she tells Rufus about her journey, explains why she thinks the medical system fails patients, and shares the simple biomarkers that you should check to see if you’re at risk for a deadly disease. 📱 This is part one of our interview with Casey. Part two will be available here on Thursday. But if you can't wait that long, you can listen right now on the Next Big Idea app: https://nextbigideaclub.com/app/

Where is AI headed, and how quickly will it get there? Should we be early adopters or keep our distance? Will it make our lives better or put us out of work? We can’t think of a better person to answer these questions than Bill Gates. He’s played a leading role in every major tech development over the last half-century, and he’s got a pretty good track record when it comes to forecasting the future. Back in 1980, he predicted that one day there’d be a computer on every desk; today on the show, he says there will soon be an AI agent in every ear. Rufus and Bill are joined by Andy Sack and Adam Brotman, co-authors of an exciting new book called “AI First.” Together, they consider AI’s impact on healthcare, education, productivity, and business. They dig into the technology’s risks. And they explore its potential to cure diseases, enhance creativity, and usher in a world of abundance. 📕 To learn more about Andy and Adam’s AI lab, Forum3, visit https://www.forum3.com. And for exclusive insights from their book, “AI First,” head to https://www.forum3.com/book 🎁 If you love the show, the best way to let us know is by becoming a Next Big Idea Club member. Learn more at https://nextbigideaclub.com/ and use code PODCAST to get 20% off your subscription